Description
What is CJC-1295 + Ipamorelin?
This research blend combines two distinct growth-hormone secretagogue peptides at a nominal 5mg + 5mg ratio. CJC-1295 is a synthetic GHRH analog; Ipamorelin is a selective pentapeptide agonist of the ghrelin/GHS-R1a receptor. The pairing is a frequently studied model system in pre-clinical somatotroph research where two complementary upstream pathways converge on the same pituitary cell population.
How CJC-1295 + Ipamorelin works (research context)
The two components act on separate but convergent receptor systems in somatotroph models. The GHRH-analog component engages the GHRH receptor, elevating cAMP via Gs-coupled signaling. The Ipamorelin component activates the Gq-coupled GHS-R1a (ghrelin) receptor, mobilizing intracellular calcium and suppressing somatostatin tone. In-vitro studies frequently document additive or synergistic GH output when both are present.
Research applications
- In-vitro modeling of synergistic GHRH/GHRP receptor cross-talk
- Pre-clinical study of pulsatile GH-secretagogue dynamics
- Comparative receptor-pathway research (cAMP vs calcium convergence)
- Reference standard for analytical characterization of blended preparations
Key facts
- Combines a GHRH-receptor analog with a selective GHS-R1a agonist
- Nominal 5mg + 5mg per-component loading per vial
- Components act through mechanistically independent, convergent pathways
- Supplied as a co-lyophilized research powder for in-vitro use
Product specifications
- Class: GHRH analog + GHRP/ghrelin-receptor agonist research blend
- Also known as: Mod-GRF + Ipamorelin blend
- Form: Lyophilized powder vial
- Purity: ≥ 99% (HPLC verified)
- Testing: Independent third-party HPLC + mass spectrometry
- Documentation: Certificate of analysis per batch
- Storage: Store lyophilized at -20C; once reconstituted keep refrigerated at 2-8C and protect from light.
For laboratory research use only. Not for human or veterinary use, consumption, diagnostic, or therapeutic purposes.
Dr. Eva Novak (verified owner) –
Consistent 5+5 loading lot to lot. cAMP and calcium readouts converged exactly as the dual-pathway model predicts.
Dr. Pierre Lefevre (verified owner) –
The co-lyophilized blend reconstituted as a clean single solution. Both components resolved on our HPLC at the expected ratio — well-formulated reference material.
Hana Yamamoto (verified owner) –
Used in somatotroph cultures — the additive GH-secretagogue response between the GHRH analog and Ipamorelin was clear and reproducible. Great blend QC.
Marcus Delaney (verified owner) –
Certificate listed both peptides separately with purities — appreciated the transparency on a blend. Reconstituted clear.
T. Mbeki (verified owner) –
Good value for a two-component vial and the COA covered both peptides. Shipping was a bit slow but well packed.