Description
What is Methylene Blue?
Methylene blue is a heterocyclic aromatic phenothiazine compound first synthesized in 1876. Beyond its classical histological staining role, it is widely studied in laboratory research as a redox-cycling agent that can accept and donate electrons at the mitochondrial level, alternating between oxidized (blue) and reduced (leucomethylene blue, colorless) states. Supplied as oral tablets for reference laboratory study.
How Methylene Blue works (research context)
In research models methylene blue acts at the mitochondrial electron-transport chain, shuttling electrons by accepting them from NADH and donating them to cytochrome c, effectively bypassing Complex I and III blockages. This redox cycling is associated with enhanced mitochondrial respiration, reduced oxidative stress, and upregulation of cytochrome c oxidase activity. It is also studied as an inhibitor of soluble guanylate cyclase and nitric oxide synthase at higher concentrations.
Research applications
- In-vitro studies of mitochondrial respiration and electron-transport chain function
- Research into cellular bioenergetics and oxidative stress mitigation
- Pre-clinical neuroprotection and cognitive-function models
- Redox-cycling and cytochrome c oxidase activity investigation
Key facts
- Phenothiazine heterocycle; first synthesized in 1876
- Alternates between oxidized (blue) and reduced (colorless) states
- Bypasses Complex I/III in mitochondrial electron-transport chain
- Supplied as 20mg oral tablets for reference research use
Product specifications
- Class: Phenothiazine redox-cycling small molecule
- Also known as: Methylthioninium chloride; MB
- Form: Oral tablets
- Verification: Identity and quality checked per batch
- Documentation: Certificate of analysis per batch
- Storage: Store tablets at controlled room temperature in a dry, light-protected container.
For laboratory research use only. Not for human or veterinary use, consumption, diagnostic, or therapeutic purposes.
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Discreet, fast, and verifiable. Exactly what I need for lab work.
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Solid quality and clear batch labeling. Packaging is sturdy and arrived with no damage.
Jordan P. (verified owner) –
Discreet packaging, cold-chain intact, arrived in two days. Support actually understands the science.
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Purity numbers held up against our own in-house HPLC check. Reliable supplier.
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Great purity and fast shipping. Labeling and batch numbers were clear and fully traceable.
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